Bioactive Ferrimagnetic Glass-ceramics for Magnetic Induction Hyperthermia

Ferrimagnetic glass-ceramics are potential candidates for magnetic induction hyperthermia [1]. The aim of this work is the preparation and characterization of innovative bioactive ferrimagnetic glass-ceramics in the system SiO2– Na2O–CaO–P2O5–FeO–Fe2O3. These biomaterials contain different amounts of nanometric or sub-micrometric magnetite crystals, homogeneously distributed in an amorphous matrix. They show bioactivity properties, making them also suitable for bone substitutions. The influence of the chemical composition and processing condition (temperature, time, atmosphere) on the glassceramics microstructure and on their properties has been analysed. The specific power loss of these biomaterials varies in the range 20-65 W/g, in function of the glassceramic microstructure. The surface of these materials can be easily modified, in order to bind specific proteins for magnetic drug targeting.